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fischer esterification > mechanisms > home      

Fischer esterification mechanism


The general form of Fischer esterification mechanism is as follows:

The first step involves protonation of the carbonyl oxygen, followed by the nucleophillic attack of the alcohol.

Then a loss and regain of a proton,

followed by loss of water as electrons from the alcohol oxygen kick down to form the double bond. Loss of a proton yields the ester.

Example of fischer esterification:



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